itd be awesome if this was the secret to adult male dry orgasms. i would takr that like birth control without even needing that for sex specifcially.
being able to do the deed without worrying about cleanup or pregnatizing anyone is the ultimate value
I mean you could take a 6 mg injection of estradiol enanthate weekly. That would produce the effects you want. Though…it…may also have some other effects…but anything’s work it for a dry climax, right? 😈 😆
/s for the dense.
I don’t think this stops liquid production, it just drastically reduces the sperm count, which is a small percentage of the ejaculation.
I’ve heard there is already something that basically makes guys shoot dry blanks, search dry orgasm pill
Uber-“straight” men should have no problem with that since they dont use it for anything 🙄
I don’t know, I find it kind of fun to make a bit of a mess. Wouldn’t mind if it was a biologically inert mess.
If anyone can figure that out without needing to remove the prostate, that would be huge. Seems like thats the actual root of ejaculation or something to that effect
I mean, you could inject say, 6 mg of estradiol enanthate weekly. That would produce dry climax for most people. Though, there may be some…undesirable side effects, depending on your perspective…
You keep leaving this comment, exactly what sort of wood scientist are you?
Only left it twice!
Oh, and the fun kind!
Think of the money we’ll save in shoe boxes!
Zero pregnacerating.
, That, too
June 29, 2010
Introducing the First Male Birth Control Pill
https://www.cosmopolitan.com/lifestyle/news/a8721/male-birth-control-pill-contraception/That’s the earliest year I remember hearing about a male birth control pill. There are probably articles from years prior to 2010. Obviously this is a great advancement, but is it reasonable to expect one of these to actually come to market within the next decade?
Edit: Actually, this is discussed in an article linked to by the Scientific American article:
A joke among researchers in the field of male contraception is that a clinically approved alternative to condoms or vasectomy has been five to 10 years away for the past 40 years.
Female birth control has to be safer and have fewer side effects than pregnancy.
Male birth control has to be safer and have fewer side effects than letting women carry the burden of birth control.
There will not be a male birth control pill. We would be better off putting these resources toward improving the safety of female birth control.
more options are always good for edge cases.
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some women can’t take birth control pills, and the other birth control options have downsides as well.
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nothing is 100% effective, so if you want to be even more sure that you won’t make babies, both pertners being sterlized is extra security.
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some men would like to be sterile but are hesitant to have a vasectomy done. They are generally simple but they don’t always go well.
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for younger single men in casual encounters, you can never be sure of the other’s birth control status. I’m sure there are men who would like the option to be in control of their sperm.
I’m not saying there shouldn’t be male hormonal birth control, it’s just that after 40 years of the same story over and over, it seems the effort should be redirected. Vasalgel has been “in development” since the 70s. It’s not getting any closer.
Meanwhile, the US still only has one size of non hormonal IUD available, and two sizes of hormonal. They don’t fit most nulliparous women comfortably. This is a very fixable problem. 50 years of R&D could have solved this.
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Male birth control has to be safer and have fewer side effects than letting women carry the burden of birth control.
I mean, I don’t think this is such a high bar to pass.
Pregnancy is bad but I’d argue the consequences of 18 years of unwilling parenthood far outstrips the consequences of 9 months of pregnancy. The consequences for those 18 years impact both parties.
Furthermore, men have almost zero agency of what happens in the case of an unintended pregnancy. A man can’t say, “this would ruin my life, I am going to choose not to have the baby.”
That makes the risk quite high for a man, IMO, and the only way to take agency over that risk is male birth control.
Male birth control has to be safer and have fewer side effects than letting women carry the burden of birth control.
This first phase study shows no side effect.
It seems you are underestimating the value for men to not be responsible for unwanted babies and to have more control of their own contraception.
At first read that came off as callous, but I see your point. I had that thought as well regarding improving female birth control. Where’s the research into a hormone-free pill for women?
It is a bit callous. I’m old enough to have seen this pop up a dozen or so times.
Every time the depression, weight gain, acne and libido changes are deemed too severe for approval and women are sitting here like… yeah, it’s all that plus increased occurrence of stroke and heart attack for us, but ok.
I actually interpreted it as callous to the suffering women endure at first read for some reason. But yeah, there’s very much an element of, “The stakes are higher for women, so they can deal with the side effects,” which is awful.
Callous or not, it’s hard to justify trials ethically for that reason. Yes, it would be better for society as a whole, even if it could potentially be worse for an individual; but is it ethically right to burn up an individual for the sake of society? And now if you’ll excuse me, I have to walk away from Omelas.
Edit: Pre-empting a question: Yes, I walk. I recognize that the trolley would be quicker.
Thing is, female birth control is easier, because female body already has mechanism that stops fertility, we just invoke it on demand. Male body basically keeps on making sperm till death. It’s usually issues with erection or something that acts like “it’s time to stop buddy” than anything else. It’s not really about male privilege, patriarchy or whatever, it’s just biology.
Condom has worked the best as physical barrier and some injectable gels in vas deferens, but they are highly impractical application wise. Most of hormonal methods didn’t work well at all.
Nether method is more complicated or more natural or “easier.” It’s fiddling with hormones to decrease fertility.
Your personal perception is that because when women are pregnant they can’t get pregnant, they should be the ones to have their hormones fiddled with, despite the risk of death, that has, thus far not been shown in male hormonal birth control. That’s got nothing to do with science.
I’m sorry to call you out, but I think you’re disregarding a valid point and establishing a false equivalence between this contraceptive method, and traditional hormone-based methods.
Please let me elaborate. This drug is not hormone-based. It works by blocking a receptor called “RAR-alpha” that exists in every cell’s nucleus, and it works as a switch that controls gene transcription - it determines what the cell eventually produces and does. The body chops up vitamin A and uses it to trigger this receptor, and we know that it plays a role in many different processes, from cell differentiation (including formation of the heart, nervous system, and white blood cells), to development (like the formation of limbs) and even cell death. Incidentally, it also plays a role in sperm production, which kinda makes sense because of how important it is for cell differentiation and development.
The body doesn’t produce a “blocker” for these receptors, which is the function that the drug in the study, YCT-529, performs. This actually mimics the loss of RARa signaling in a vitamin A deficiency, which unsurprisingly, causes fertility problems (among a host of other symptoms).
This is a different approach from “traditional” hormonal contraception, where the most common pills (progesterone only or progesterone-estrogen) activate the same receptors that the body usually activates (and this is what the person above you was referring to) - but in way that prevents the regular cycle from progressing. The fact that the body has these “natural levers” that regulate this process is the reason why birth-control pills have existed for decades - we just push those buttons harder (I’m not denying there are consequences to this, I’m just pointing out the buttons exist). There is no such mechanism for sperm production however, so scientists have been looking at all steps that lead to sperm being produced trying to find something they can block, and that hopefully won’t have terrible consequences elsewhere.
I 100% agree that calling either method “more complicated” or “more natural” or “easier" is wrong. But we cannot gloss over the fact that this drug is a compound that is novel to the human body, and that it works through mechanisms that we only have a limited understanding over, while the other is inherently less risky (because most of its effects are to mimic the body’s normal responses) and, at this time, much better understood.
Hopefully this will prove to be a very safe and effective drug, and that responsibility for contraception is equally divided because of it, but this needs to be proven first.
Also sorry for the wall of text, but it’s kinda in my ballpark so I sort of ran with it.
Except there are many women who would like to get pregnant and trap the sperm doner into child support. I think many men would love to be in charge of their futures. Condoms can fail or be sabotaged.
Edit: Downvote me all you want but in the name of equality there should be options for males to take if they want to give their female partners the choice not to take anything. Not saying women don’t deserve better options but there should be options for males too.
Could it be the first one to pass this test phase?
To study the safety of YCT-529 in humans, we conducted a Phase 1a clinical trial where 16 healthy men received either placebo or escalating single doses of YCT-529 to assess its safety and tolerability. YCT-529 was well tolerated, and no adverse effects were noted. The positive results from this first clinical trial laid the groundwork for a second trial, where men receive YCT-529 for 28 days and 90 days, to study safety and changes in sperm parameters.
It looks like the hormonal NES/T male contraceptive gel passed safety a while back and started phase 2 trials in 2018. It’s already gearing up for phase 3 trials with investors ready to fund this final phase:
https://www.einpresswire.com/article/835140008/contraline-exercises-license-option-for-nes-t-the-first-male-contraceptive-to-reach-late-stage-developmentBut a hormone-free option is more appealing. I hope YCT-529 makes it to the finish line.
In the first clinical trial of its kind, a nonhormonal oral contraceptive that reversibly stops sperm production has just been deemed safe for human use…The trial did not assess the pill’s efficacy in reducing sperm
Uh, lol…I have to admit, I’m not really going to start caring about whether it’s safe until I know that it actually does what it’s trying to do.
How can you even honestly say it’s a “contraceptive that reversibly stops sperm production” without qualification, if you haven’t even determined it fucking works, yet?
This how medical studies work, because of ethics. First they prove it works on animals, which they did with great success. But before testing it works on humans, they must first confirm it is not dangerous, before they can ethically test for actual efficacy on a larger cohort.
I understand that’s the sequence of events, but, my point is that this isn’t worthy of a headline, not yet.
A safe drug that doesn’t work doesn’t matter. It only matters once it’s proven safe and effective.
It was successful on other primates, the chance that it will work exactly the same on humans is very high and worth the headline.
They know it works, but not how well it works
People in power want more babies
gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme gimme
No baby after midnight
Same, sign me up.
Imma just wait until they let me inject a boba ball into my nutsack.
Reversable, safe, effective, no hormonal effects. Why would I fuck with a pill?
Because this seems more invasive and according to the article, it was not yet peer reviewed.
Every solution will have a different balance of risks and benefits, more choice is good.
If it’s affective with low side effects, great! Vasectomies aren’t without consequence. VPS sucks and the best fix for it if it’s chronic is spermatic cord denervation which is costly and unpleasant surgery.
I feel like i could never trust this even if i was on it.
Would you trust it less than the female birth control pills?
No. But I also dont trust female birth control pills. I’m vaguely aware of the side effects and hormonal shifts, and I don’t think I want that in my life.
The big point of this one is that it is not hormonal, and so far this study shows no side effects. So for a couple, it could be the pill with least side effects overall.
of course nothing is 100% effective, not even condoms. consider each an additional layer of security.
So i should triple wrap?
Sure, but is the additional security worth the sides? I could wear a medieval suit of armor around all day to be safer, but it would be extremely inconvenient.
That’s the nice thing about having more contraceptive options on the market, you are more likely to find an option with minimal side effects for you and/or your partner.
I cant argue with this point
Good! You shouldn’t. If you’re trying to not have children, you should be on birth control, or partner should be in birth control, and you should use condoms.
I’ve been there done that, lol. I’m old and already did the contraception and condoms long ago. Have 2 children now, do not want more. It sounds like a nice alternative to snipping, but I just can’t trust it. We are fine, and im sure menopause is not far away for her.
It sounds like a nice alternative to snipping,
Don’t fear the snip.
I think it’s mostly a matter of being quasi irreversible rather than fear of surgery. That’s a huge decision to take if you don’t have children.
True. AFAIK the procedure itself is irreversible, but you can still have kids with in vitro if you dumb your mind.
🎶All our times have come
Here, but now they’re gone
Seasons don’t fear the snipper
Nor do the wind, the sun, or the rain 🎶
Don’t fear the snip. Mine was almost entirely painless and it’s really nice to have one less thing to worry about.
Only side effect is now my right testicle dangles lower than my left.
Agreed. I was hoping for vasalgel work out, got tired of waiting, and got the snip.
There’s lots of anecdotal evidence that orgasms are actually better afterwards. I tend to agree, but it’s something that’s
easyhard to study properly. Edit: god, that was bad wording.I think the orgasms are better because you don’t have the worry of pregnancy
I dunno, I get better orgasms when jerking off, too. But again, hard to say for sure.
Guys will do anything rather than cut off their own balls
I’m pretty sure conservatives are mad that some men actually are.
men?
yes, conservatives think that men are cutting their balls off
oh, you mean trans women? Since men get their testes removed from cancer and other reasons, it’s the misogyny and homophobia that seems to motivate the anti-trans sentiment, at least it seems.
I mean, yeah. But getting a couple of tubes inside them snipped was pretty easy.
Why would anyone in their right mind cut off their own balls?
That’s beyond Jackass levels and into the realm of Darwin awards.I think it’s a joke
Ya never know with these lemmytes…
Dude it’s not even that. I got the snip, I was back rocking in the sack 5 days later. Kids mom at the time had to give me shit ton of BJs and hand jobs. Because even week later you can still have live sperm in your sack.
male liberation?
Just be ugly lmao
This will just result in more republican births since they seem to think they are in some breeding war and won’t use it.
What a completely useless comment.
“They won’t use it anyway” does not in any way mean that births will increase. At most, they’d remain consistent.
Conservative men won’t use it. Liberal men will. You misunderstood they to mean men as opposed to republicans.
As long as Christians hold money and power this isn’t ever coming out.
But… want… :c
There’s more than the USA.
Is there anywhere not under attack from conservative religious freaks?
There are attacks in every country, but I don’t think there is any developed country where they managed to influence the state as much as in the USA.
Compliance ain’t gonna happen. Try getting a dude to take something regularly that isn’t a painkiller. Let’s mix it with advil.
I dunno, I think “take this pill every day and you’ll never have to pull out again” is a pretty convincing argument to that type of dude.
Responsible Lemmy users aside, the general public may surprise you — the stories I get from my outpatient healthcare-worker spouse are abysmal enough
Also just solo. No mess is like back to those careless days where there was no mess and you could do it like 2-3 times
Needlessly sexist and idiotic as a dude who takes medication daily.
If this lets you jackoff totally dry as long as you take it, i cant see why any dude would not be all over that like white on rice. Its literally the dream
Ejaculation sucks
No it does not, often making a mess on her and seeing her swallow it (or him if that’s your thing) is part of the fun. I’ll shoot messy blanks on and in her all day.
